The San Francisco 49ers will be without Brock Purdy for their TNF matchup with the Los Angeles Rams. Nick Wright, Chris Broussard, Kevin Wildes, and Eric Mangini ask if the 49ers are in trouble without Purdy, and if the Baltimore Ravens should have John Harbaugh on the hot seat.

NFL Week 5 is here and we’ve got the best NFL bets you need to know! Chris “Bear” Fallica, Geoff Schwartz, and Sammy Panayotovich break down their Top 5 NFL bets to place right now. Which WRs will lead the week in the receiving yards and which QB will lead the week in passing yards?! If you’re looking for NFL Week 5 best bets, betting predictions, picks against the spread, and prop plays, this is your ultimate guide. Don’t place your wagers without hearing what your favorite gambler’s favorite gamblers have to say!

With freshman Bryce Underwood leading the charge, Michigan is eyeing a statement Big Ten win, but a desperate Wisconsin squad could have other plans.

We're tracking the latest on what's happening around the NFL heading into Week 5 of the 2025 season.

Philadelphia Eagles WR A.J. Brown said that he doesn’t think it’s a bad thing for wanting the ball. Nick Wright, Chris Broussard, and Kevin Wildes ask if the Eagles’ offense is sustainable. Plus, they discuss Deion Sanders defending Shedeur Sanders’ pantomime press conference.

Josh Allen sat down with Mark Sanchez to discuss the broken nose he received during Week 3 of the NFL season.

Will rookie Dillon Gabriel help the Browns upset the Vikings in London? Find out what the betting trend says about their chances.

Will Hill delivers another edition of "Will's Wagers" — his favorite bet from every NFL game. Check out where he's laying his money in Week 5.

Duke has signed head coach Jon Scheyer to a two-year extension, which runs through the 2030-31 college basketball season.

NFL Commissioner Roger Goodell says the league plans to soon launch women’s and men’s professional flag football leagues.

FanDuel Sportsbook Bonus: How to Bet on the Rams vs 49ers on Thursday Night Football.

NBA free agency officially opened on June 30, and teams have already secured deals with some of the biggest names on the open market.

Shohei Ohtani will make his postseason pitching debut when he starts for the Dodgers against the Phillies in Game 1 of the NLDS.

FanDuel TNF Bonus: Bet $5, Get $300 If Your Rams vs 49ers Thursday Night Football Bet Wins.

The Commanders both love and fear their spectacular second-year quarterback's playing style. So how do they keep him upright?

FanDuel Sportsbook TNF Promo: Bet $5, Get $300 if Your Teams Wins in the Rams-49ers Thursday Night Matchup.

Chiefs owner Clark Hunt told "First Things First" that Patrick Mahomes threw a no-look pass during his rookie season, causing the team to think they had something special at QB.

FOX Sports NFL Draft analyst Rob Rang ranks the top pass-catchers in the 2026 class.

FOX Sports' Urban Meyer joins Colin Cowherd to discuss James Franklin's 4-21 Top 10 record, along with how far Alabama will go after big upset win over Georgia. He then breaks down Julian Sayin's freshman season so far, along with whether Miami is a legit National Championship contender or not and if Dante Moore is the best QB in CFB.

Here are the top moments and highlights from all the Game 3 action across the MLB wild-card round on Thursday.

Caitlin Clark says Cathy Engelbert hasn’t reached out to her in the aftermath of Napheesa Collier’s statement revealing what the WNBA commissioner allegedly said about Clark.

Joel Klatt previewed the Miami Hurricanes vs. Florida State Seminoles. He questioned if Miami can get their third ranked win in an ACC rival game. Joel explained how the bye week could benefit Miami going into this rivalry game. He also previewed the Wisconsin Badgers heading to Ann Arbor to take on the Michigan Wolverines.

The Boston Red Sox will play the New York Yankees in game 3 of the AL Wild Card. Colin Cowherd asks who will win this matchup of two teams desperate to advance to the next round.

The Los Angeles Dodgers swept the Cincinnati Reds in the NL Wild Card. Colin Cowherd asks if the Philadelphia Phillies are next to be brushed aside.